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NFL Week 6 Odds Breakdown

Earnest Horn
Written by Earnest Horn
October 11, 2023
NFL Week 6 Odds Breakdown

Nearing the mid-way of the 2023 NFL season, the Super Bowl contenders are beginning to emerge from the crowded field while numerous teams still have hopes of making a deep playoff run.

With only four games featuring divisional rivals, bettors have multiple lopsided games on this slate as five contests feature spreads of seven or more points in Week 6.

Denver Broncos at Kansas City Chiefs (-10.5) Thursday 8:15pm

Week 6 kicks off with an AFC West rivalry game featuring two teams headed in opposite directions. The Kansas City Chiefs (4-1) have not lost since a season-opening setback against Detroit.

The Denver Broncos, meanwhile, have 28 or more points four consecutive weeks, winning only once during that span. This game has an over/under starting at 47.5 points.

Baltimore Ravens (-4.5) at Tennessee Titans Sunday 9:30am

The Baltimore Ravens (3-2) and Tennessee Titans (2-3) will finalize the three-game London swing this season on Sunday.

Baltimore is fourth in the NFL this season in rushing yards and faces a Titans team that has yielded less than 95 yards per contest through five weeks. The Ravens/Titans game features a total over/under mark of 40.5 points.

Minnesota Vikings (-2.5) at Chicago Bears 1pm

For the 125th time, the Minnesota Vikings (1-4) square off against the Chicago Bears in a NFC North Week 6 contest Sunday. Minnesota limps into this contest having lost Justin Jefferson for the foreseeable future to injury in last week’s 27-20 defeat against Kansas City.

Chicago played last Thursday, getting two additional days of rest after their convincing 40-20 victory over Washington. This game features an over/under line of 44.5 points.

Indianapolis Colts at Jacksonville Jaguars (-4.5) 1pm

An AFC South battle for first place takes place in Jacksonville during Week 6 when the Indianapolis Colts (3-2) travel south to take on the Jaguars (3-2).

Indianapolis has won three of four games, including Week 5’s victory over the Tennessee Titans. Jacksonville, meanwhile, returns stateside after back-to-back games in London. The over/under points total starts at 45.5 points in 2023.

Seattle Seahawks at Cincinnati Bengals (-2.5) 1pm

Bengals QB Joe Burrow faces off against the Seahawks for the first time in his career Sunday when Cincinnati (2-3) hosts Seattle (3-1) in Week 6.

The Bengals snapped their losing skid with a 34-20 victory over the Arizona Cardinals last week while Seattle – winners of three straight – enjoyed an early bye week. This game’s over/under total starts at 45.5 points.

Carolina Panthers at Miami Dolphins (-13.5) 1pm

For the second straight week, Carolina (0-5) is a two-score underdog when the Panthers hit the road to take on red-hot Miami (4-1) Sunday. The Dolphins last week eclipsed the 2000 Rams’ record for yardage through five games and have amassed more than 2,500 yards through Week 5.

Carolina – with new QB Bryce Young – have nearly 1,000 yards in their winless campaign. The over/under for this game is the second-highest of Week 6 at 48.5 points.

New Orleans Saints (-1.5) at Houston Texans 1pm

For only the sixth time in franchise history, the Houston Texans (2-3) face the New Orleans Saints (3-2) Sunday. Houston has never won inside of the Caesars Superdome, building some intrigue in QB C.J. Stroud’s first-ever visit.

Entering Week 6, New Orleans snapped their two-game slide with a 34-0 drubbing of New England. This game’s over/under total starts at 42.5 points.

San Francisco 49ers (-5.5) at Cleveland Browns 1pm

Undefeated San Francisco (5-0) travels to Cleveland (2-2) looking to keep their winning streak intact during this Week 6 matchup. The 49ers have won in convincing fashion, including their last outing by blasting the Dallas Cowboys 42-10 Sunday night.

The Browns enter off a bye week, giving Cleveland extra opportunity to gameplan for the 49ers. This over/under total is Week 6’s lowest at 37.5 points.

Washington Commanders at Atlanta Falcons (-2.5) 1pm

The Washington Commanders (2-3) take a trip south this weekend to face the Atlanta Falcons (3-2). Washington has lost three straight games, including an embarrassing 40-20 defeat to the then-winless Chicago Bears on Thursday night.

Atlanta enters the game with a perfect 3-0 record at home, but two of the three wins were by a combined three points. This game’s over/under total starts at 42 points.

New England Patriots at Las Vegas Raiders (-3) 4:05pm

Bill Belichick and the New England Patriots (1-4) return to Las Vegas for a second straight year to face off against former assistant – and now head coach – Josh McDaniels and his Las Vegas Raiders (2-3).

McDaniels has beaten New England twice – once in 2022, and again in the pre-season this year. The over/under total on this game is set at 41.5 points.

Detroit Lions (-3) at Tampa Bay Buccaneers 4:25pm

Two surprising outright divisional leaders square off when the Detroit Lions (4-1) face the Tampa Bay Buccaneers (3-1) Sunday afternoon. The Lions have been paced by RB David Montgomery and his 420 yards of total offense.

Coming off a bye week, Tampa Bay sports the third-best scoring defense in the league, having only yielded 17 points each outing. With that in mind, the Buccaneers and Lions enjoy an over/under total of 43.5 points.

Philadelphia Eagles (-7) at New York Jets 4:25pm

The NFL’s other undefeated team – the Philadelphia Eagles (5-0) – head north this weekend to square off against the New York Jets (2-3). The Eagles rank second in rushing this season, averaging over 160 yards per contest on the ground.

New York, meanwhile, has the league’s fourth-worst rushing defense as the Jets have surrendered over 145 yards per outing on the ground. The over/under total for this contest starts at 41 points.

Arizona Cardinals at Los Angeles Rams (-6.5) 4:25pm

A NFC West showdown between teams fighting to avoid the division’s cellar occurs when the Los Angeles Rams (2-3) host the Arizona Cardinals (1-4).

The Rams are looking for their first home victory of the season while the Cardinals have yet to win away from home. The over/under total on this game starts at 48.5 points.

New York Giants at Buffalo Bills (-14) 8:20pm

On paper, the New York Giants (1-4) are massive underdogs to the home-standing Buffalo Bills (3-2). The difference, however, is Buffalo is just returning home from their London series game, a contest Jacksonville earned the upset against the Bills.

New York limps into this contest with an injured QB (Daniel Jones) and a star RB (Saquon Barkley) either returning from or leaving for an opportunity. This game features the second-largest over/under total at a48.5 points.

Dallas Cowboys (-1.5) at Los Angeles Chargers Monday 8:15pm

Two teams with a lot to prove face off Monday night when Dallas (3-2) heads to Los Angeles for a tilt against the Chargers (2-2).

The Cowboys comes into the game off their 42-10 wrangling Sunday night against San Francisco while the Chargers enjoyed an early bye week. This game has the highest over/under total for Week 6 at 50.5 points.

Bye week: Green Bay Packers, Pittsburgh Steelers

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