The reign of the 1972 Dolphins will continue for another year after both Philadelphia and San Francisco were defeated during Week 6 action.
This is the earliest the last NFL franchise has lost their first game since 2014 when three undefeated teams were tamed during Week 3.
With injuries again playing tricks on multiple teams before Halloween, what treats await bettors for NFL Week 7?
NFL Week 7 kicks off with an intriguing matchup as the Jacksonville Jaguars (4-2) head to New Orleans to face the Saints (3-3).
While Jacksonville emphatically won their last outing, reports have QB Trevor Lawrence listed as day-to-day with a knee injury.
New Orleans – fresh off a 20-13 loss to the Houston Texans – will look to get above .500 for the third time this season. This game opens at 39.5 points on the over/under line.
A pair of teams needing wins to stay in their respective division races meet Sunday when the Cleveland Browns (3-2) travel to take on the Indianapolis Colts (3-3).
The Browns enter as a confident bunch, having just taken down previously undefeated San Francisco in Week 6.
The Colts were soundly defeated last week by Jacksonville and continue to rely on Gardner Minshew with QB Anthony Richardson placed on the IR list. This contest’s over/under total starts at 39 points.
AFC East rivals square off when the Buffalo Bills (5-1) make the trek to Gillette Stadium to take on the New England Patriots (1-5).
The Bills have owned the series as of late, winning six of the last seven contests between these two.
New England has lost three straight contests, including Sunday’s 21-17 defeat to the Las Vegas Raiders. This game has an over/under total starting at 41.5 points.
Two proud franchises looking to rebuild this season face off when the Las Vegas Raiders (3-3) take on the Chicago Bears (1-5).
After a three-game losing streak, Las Vegas has evened their record behind strong defensive performances the past two weeks.
The Bears look to be without their starting QB and RB for the next few weeks, leaving their offense in disarray heading into this Week 7 matchup. This game’s over/under total is the week’s lowest, starting at 37.5 points.
NFC East rivals collide in the Big Apple as the Washington Commanders (3-3) face the New York Giants (1-5).
The Commanders evened their record last week with a victory over the Atlanta Falcons.
New York, meanwhile, lost their second primetime contest of the season against the Buffalo Bills, their fourth consecutive loss of the season. The over/under total for this game starts at 39.5 points.
Speaking of the Atlanta Falcons (3-3), they head south Sunday to take on NFC South divisional rival Tampa Bay (3-2) in a matchup that will determine who has possession of first place.
Atlanta QB Desmond Ridder will look to rebound past his three-INT showing against the Commanders while the Buccaneers offense was stymied in a 20-6 throttling by the Detroit Lions.
This NFL Week 7 contest features an over/under total opening at 38 points.
A red-hot Detroit Lions (5-1) team heads into Baltimore this weekend to face the Ravens (4-2).
In the best matchup this week, the Lions will rely QB Jared Goff to move the ball down the field.
Baltimore’s contrasting style will focus on using the run game to set up easier passes for QB Lamar Jackson downfield. This over/under total starts at 42 points.
An NFC West showdown between two rivals takes place Sunday when the Arizona Cardinals (1-5) travel north to face the Seattle Seahawks (3-2).
Both teams are looking to get back into the win column after losing games in Week 6.
Seattle looks to get back on track offensively after being shut out in the second half against the Bengals while Arizona continues to seek an offensive identity without QB Kyler Murray. The over/under total for this game starts at 44.5 points.
The Pittsburgh Steelers (3-2) travel across the country to Los Angeles to face the Rams (3-3).
Pittsburgh got back into the win column Sunday against the rival Ravens while Los Angeles also secured a 26-9 victory over their rivals from Arizona.
Both teams enter the contest remarkably healthy, especially with Pittsburgh coming off a bye week. This contest’s over/under total starts at 44 points.
The Green Bay Packers (2-3) travel to Denver for a Week 7 matchup against the Broncos (1-5). Denver’s historically bad defense has surrendered a league-worst 33.3 points per game this season.
Conversely, Green Bay’s offense has scored over 30 just once this year during their season-opener against Chicago’s third-worst scoring defense.
The over/under total for this contest comes in at 45 points, a line that will draw heavy bets this week.
When the Los Angeles Chargers (2-3) travel to Kansas City this week, the Chiefs (5-1) will look to add to their league-leading win total.
The Chargers average Top 10 offensive statistics in yards per game (365), points (25.4) and passing yards (259.5).
Defensively, the Chiefs are also averaging Top 10 figures in yards per game (284), points (14.7) and passing yards (183.8). In a matchup featuring opposing strengths doing battle, this over/under total starts at 48 points.
The marquee game for Week 7 features the Miami Dolphins (5-1) traveling to Philadelphia to take on the Eagles (5-1). The Dolphins’ lone loss was against Buffalo earlier this month, a 48-20 beat-down by their AFC East rivals.
Philadelphia was the last undefeated team prior to dropping a Week 6 game to the New York Jets in a game in which the Eagles offense turned over the ball an uncharacteristic four times.
Unsurprisingly, this over/under total is starting at 52 points – the NFL Week 7’s highest – with two high-powered offenses squaring off.
The Monday Night Football game this week features the San Francisco 49ers (5-1) playing at the Minnesota Vikings (2-4).
Despite their record, Minnesota has been in every game, losing by no more than seven points in any game.
Despite losing last Sunday, the 49ers own the league’s best point differential at +16.2 points and by +9.3 point in road games. This over/under total starts at 44 points.
Bye Week: Carolina Panthers, Cincinnati Bengals, Dallas Cowboys, Houston Texans, New York Jets, Tennessee Titans