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NFL Week 10 Odds

Earnest Horn
Written by Earnest Horn
November 7, 2023
NFL Week 10 Odds

While the kick-off and send-off games for the NFL’s Week 10 slate aren’t appetizing for most fans, several games on this week’s schedule have ramifications on playoff positioning.

With three divisional leaders on byes this week, which teams below them in the standings can make a move for the top spot? Discover that and more in the Week 10 NFL Odds breakdown.

Carolina Panthers at Chicago Bears (-3.5) Thursday 8:15pm

By Friday morning, either the Carolina Panthers (1-7) or the Chicago Bears (2-7) will join Arizona as the league’s second team with eight losses. The Bears have lost two straight, including a 24-17 defeating Sunday by the NFC South leading Saints.

A second-quarter meltdown doomed the Panthers against the Colts Sunday, leading to a 27-13 defeat. The over/under total for this game is starting at 40 points.

Indianapolis Colts (-1) at New England Patriots Sunday 9:30am

The final International series contest this year belongs to the Indianapolis Colts (4-5) and the New England Patriots (2-7). Colts RB Jonathan Taylor is leading the charge, averaging 77 total yards per outing in 2023.

The Patriots have lost two straight, including a disheartening 20-17 loss to Washington last Sunday. This Week 10 matchup has an over/under starting at 43.5 points.

San Francisco 49ers (-3) at Jacksonville Jaguars 1pm

Two teams coming off bye weeks collide when the NFC West leading San Francisco 49ers (5-3) face off against the AFC South leading Jacksonville Jaguars (6-2). The 49ers have lost three straight games, two of those three losses by a combined seven points.

The Jaguars are riding a five-game winning streak, the longest active streak in the NFL. This game’s over/under total is starting at 45 points.

Tennessee Titans at Tampa Bay Buccaneers (-1) 1pm

Teams in search of their fourth win this season face off in Florida when the Tennessee Titans (3-5) take on the Tampa Bay Buccaneers (3-5) in this Week 10 matchup. The Titans are on their second stop of a three-game road swing, losing their first game against Pittsburgh 20-16 last Sunday.

The Buccaneers are on a four-game losing streak, highlighted by 39-37 loss Sunday to Houston. This game’s over/under total starts at 38 points.

Cleveland Browns at Baltimore Ravens (-6) 1pm

The Cleveland Browns (5-3) are one of three teams 1.5 games behind the AFC North leading Baltimore Ravens (7-2). Cleveland’s dynamic defense is hot, helping the Browns earn a 27-0 victory over Arizona last Sunday.

The Ravens are riding a four-game winning streak, owning wins over two NFC divisional leaders. With a pair of NFL leading defenses on display, this game’s over/under is surprisingly set at 38.5 points.

Houston Texans at Cincinnati Bengals (-7) 1pm

Winners of four of their last six contests, the Houston Texans (4-4) are riding the arm of QB C.J. Stroud. The rookie set the NFL record Sunday with 470 passing yards and five total TDs, demonstrating his hot hand entering the game against the Cincinnati Bengals (5-3).

The Bengals are winners of four straight games, however, with three wins over NFC West teams. This game’s over/under total begins at 46.5 points.

New Orleans Saints (-2.5) at Minnesota Vikings 1pm

Two teams on multi-game winning streaks square off when the New Orleans Saints (5-4) face the Minnesota Vikings (5-4). The Saints are leading the NFC South after claiming a win last week over Chicago.

The Vikings, meanwhile, trail the Lions by 1.5 games and need a victory this week to continue jockeying for a playoff spot. This game’s over/under total is set at 41 points.

Green Bay Packers at Pittsburgh Steelers (-3) 1pm

The Green Bay Packers (3-5) snapped a four-game losing streak by beating the Los Angeles Rams Sunday. This week, the Packers travel to Pittsburgh to face the Steelers (5-3).

Pittsburgh made a late TD pass from QB Kenny Pickett stand in their 20-16 victory over the Titans Sunday. This contest’s over/under total is set at 37.5 points.

Atlanta Falcons (-1) at Arizona Cardinals 4:05pm

The Atlanta Falcons (4-5) last-minute collapse against the Vikings negated their best offensive performance in weeks, losing 31-28 to Minnesota in Week 9. Arizona, meanwhile, is a mess; the Cardinals (1-8) have yet to name their starting signal caller for this game and could be poised to return QB Kyler Murray to the field.

With significant uncertainty surrounding this contest, oddsmakers have started the over/under total at 42.5 points.

Detroit Lions (-1.5) at Los Angeles Chargers 4:05pm

Coming off a bye week, the Detroit Lions (6-2) are leading the NFC North division, a title Detroits hasn’t claimed since 1993.

Their opponent this week is the Los Angeles Chargers (4-4), a team that has won two straight contests. At 49 points, this matchup features the highest over/under total of any Week 10 game.

New York Giants at Dallas Cowboys (-17) 4:25pm

With news that QB Daniel Jones is finished this season, the New York Giants (2-7) are facing the largest points spread this season in their second game against the Dallas Cowboys.

This time, Dallas hosts the game after pummeling the Giants 40-0 in both team’s season-opener. This contest, however, shows an over/under total starting at 39 points.

Washington Commanders at Seattle Seahawks (-6.5) 4:25pm

Washington comes into their Week 10 contest with QB Sam Howell earning an opportunity to win the job for the foreseeable future. The Commanders (4-5) have a chance to build on that future against the Seattle Seahawks (5-3).

Seattle will be looking to erase the memories of their Week 9 loss, a 37-3 drubbing by the Baltimore Ravens. This game’s over/under total starts at 45 points.

New York Jets (-1.5) at Las Vegas Raiders 8:20pm

Sunday’s night-cap for the NFL Week 10 slate is the New York Jets (4-4) traveling to Nevada for a game against the Las Vegas Raiders (4-5). New York relies on their defense as QB Aaron Rodgers alludes to returning this season.

The Raiders – a week after firing their head coach and front office – looked relevant again in a 30-6 beatdown of the New York Giants. This game’s over/under total is the lowest of the week, starting at 36 points.

Denver Broncos at Buffalo Bills (-7.5) Monday 8:15pm

The Monday Night primetime game features the Denver Broncos (3-5) against the Buffalo Bills (5-4). Denver enters the game having won two straight and will be rested after a well-placed Week 9 bye.

The Bills have split their last six contests and need a win to keep pace with the AFC East leading Dolphins. This game’s over/under total starts at 47 points.

Bye Week: Kansas City Chiefs, Miami Dolphins, Philadelphia Eagles, Los Angeles Rams

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