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NFL Week 4 Odds Breakdown

Earnest Horn
Written by Earnest Horn
September 26, 2023
NFL Week 4 Odds Breakdown

Six intra-division contests highlight the NFL’s Week 4 schedule, including multiple contests that will determine first place for that division. This is also the last time every team will be in action each Sunday for the next two months as every team’s easiest opponent – the bye week – begins in Week 5.

Detroit Lions (-1.5) at Green Bay Packers, Thursday 8:15pm

A NFC North battle for first place unfolds Thursday night when Green Bay (2-1) hosts Detroit (2-1). The Packers rallied from 17-0 to squeak out a win over New Orleans while the Lions easily bested previously undefeated Atlanta in Week 3. The over/under for this contest is starting at 45.5 points.

Atlanta Falcons at Jacksonville Jaguars (-3), Sunday 9:30am

Two teams looking to end losing streaks meet up in Week 4 when Atlanta (2-1) and Jacksonville (1-2) travel to London Sunday. The Falcons dropped their first contest of the season in Week 3 while the Jaguars fell in embarrassing fashion to the Texans 37-17. This early-morning game is starting at 43.5 points for the over/under odds.

Los Angeles Rams at Indianapolis Colts (-1.5), 1pm

Two teams heading in opposite directions collide in Indianapolis Sunday when the Colts (2-1) host the Los Angeles Rams (1-2). Indianapolis has won two straight, including an OT thriller against Baltimore in Week 3. Los Angeles, meanwhile, has lost two straight, including a stinging 19-16 defeat in Cincinnati Monday night. The over/under starts at 45.5 points.

Baltimore Ravens at Cleveland Browns (-2.5), 1pm

Supremacy in the AFC North is on the line when a pair of 2-1 teams take the field in Ohio. Baltimore dropped their first game of the season with a 22-19 OT loss to the Colts last Sunday while Cleveland rebounded to blow out the Titans 27-3 in Week 3. Oddsmakers expect a defensive struggle as this game starts at 41.5 over/under total points.

Minnesota Vikings (-3.5) at Carolina Panthers, 1pm

Two winless teams meet in Carolina (0-3) Sunday when the Panthers host the Vikings (0-3). Minnesota is favored by virtue of a dangerous offense, especially after the Vikings added former LA Rams RB Cam Akers via trade late last week. This contest’s over/under wager starts at 45.5 points.

Cincinnati Bengals (-2.5) at Tennessee Titans, 1pm

When Cincinnati (1-2) faces Tennessee (1-2) in Week 4, the game will come down to which team’s strength is greater than their own weakness. The Bengals are surrendering the second-most rushing yards in the NFL, a soft spot Derrick Henry and company can take advantage of Sunday. Conversely, the Titans have allowed the fifth-highest passing total through three games, a weakness Joe Burrow and Ja’Marr Chase can exploit. The over/under for this contest starts at 43.5 total points.

Tampa Bay Buccaneers at New Orleans Saints (-3), 1pm

Another NFC divisional fight for first place happens in Week 4 when Tampa Bay (2-1) heads to New Orleans (2-1). The Buccaneers have a short week to recoup from their first loss – a 25-11 thumping by Philadelphia – while the Saints blew a 17-point lead in the fourth quarter to lose to the Packers. A week-low 39.5 total points is the starting over/under wager for this game.

Miami Dolphins at Buffalo Bills (-2.5), 1pm

The undefeated Dolphins (3-0) will look to maintain the NFL’s hottest offense when they tangle with a fellow Super Bowl contender in Buffalo (2-1). Miami’s top-ranked passing offense will look to give the Bills – the fifth-best passing defense in the league – fits in Week 4. This matchup has the highest over/under total, starting at 53.5 points.

Denver Broncos (-3.5) at Chicago Bears, 1pm

The worst defenses in the NFL collide when Denver (0-3) heads to Chicago (0-3) for a Week 4 matchup. Through three games, both the Broncos and the Bears have yielded 106 or more points, including Denver’s historic 70-point showing Sunday against the Dolphins. The over/under – unsurprisingly – is among the highest this week with 46 points total.

Washington Commanders at Philadelphia Eagles (-7.5), 1pm

Few teams enter this Week 4 matchup hotter than the Philadelphia Eagles. As one of three undefeated teams remaining in the NFL, the Eagles (3-0) look to build more momentum Sunday with a victory against Washington (2-1). After two wins to open the year, the Commanders were decimated 37-3 in their last outing against the Buffalo Bills. This game has an interesting over/under total, starting at 44.5 points.

Pittsburgh Steelers (-3) at Houston Texans, 1pm

Two teams with young starting QBs face off in Week 4 as the Pittsburgh Steelers (2-1) head to Houston to take on the Texans (1-2). Second-year starter Kenny Pickett leads Pittsburgh’s balanced offensive attack while Houston relies heavily on top draft pick C.J. Stroud in a pass-first offense. The over/under total for this contest starts at 41 points.

Las Vegas Raiders at Los Angeles Chargers (-6), 4:05pm

Two teams desperate for a win meet Sunday when the Las Vegas Raiders (1-2) head to their former home to face the Los Angeles Chargers (1-2). After a season-opening win against Denver, Las Vegas has dropped two straight games. The Chargers, meanwhile, finally punched into the win column last week with their 28-24 victory over a winless Minnesota franchise. Any game featuring the Chargers will have an elevated over/under wager with this game starting at 47.5 points.

Arizona Cardinals at San Francisco 49ers (-14), 4:25pm

Can Arizona (1-2) pull another upset when the Cardinals travel to San Francisco (3-0) in Week 4? After defeating the Dallas Cowboys as 13-point underdogs, Arizona has another chance as 14-point underdogs to the 49ers. San Francisco has won every game this season by at least seven points. The over/under total for this game starts at 43.5 points.

New England Patriots at Dallas Cowboys (-7), 4:25pm

Another tale of two teams headed in opposite directions will unfold Sunday in Texas. New England (1-2) finally broke into the win column in Week 3 by beating the New York Jets for the 15th consecutive time. Meanwhile, Dallas (2-1) was upset as double-digit favorites in their last outing. With two teams that lean into their defensive efforts matching up, the over/under for this game starts at 42.5 points.

Kansas City Chiefs (-9.5) at New York Jets, 8:20pm

The Sunday primetime tilt features the Kansas City Chiefs (2-1) heading north to face the New York Jets (1-2). Kansas City hit its stride against Chicago in Week 3, easily dispatching the Bears 41-10. For New York, nothing has been easy after losing QB Aaron Rodgers four plays into the Jets’ season. The over/under for this contest starts at 42.5 points.

Seattle Seahawks at New York Giants (-1.5), Monday 8:15pm

For the second time in as many days, New York will be the host of the featured primetime NFL game. The Giants (1-2) could have RB Saquon Barkley back this week to face the Seattle Seahawks (2-1) and their pass-oriented offensive attack. Oddsmakers have set the over/under for this contest at 46.5 points.

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