College Football Week 2 Betting Guide: 4 Best Bets for Saturday, September 6

Get locked and loaded for college football’s Week 2 slate by diving into our betting guide. Our CFB expert has 4 best bets for Saturday, September 6. Enjoy the action, and best of luck with all of your investments.

Saturday, September 5 at 4:15 PM	Spread	Money	Total
Northern Illinois Huskies	+30.5 (-115)	+3500	O 45.5 (-105)
Iowa Hawkeyes	-30.5 (-110)	-20000	U 43.5 (-108)

Best Bet: Iowa vs Iowa State UNDER 41.5

Iowa is coming off a 34-7 win at home over Albany. They struggled and led just 17-7 at the half. They threw the ball just 16 times all game but the run game was on point. 7 different ball carriers combined to gain over 300 yards on the ground. Defensively, they held Albany to just 2 conversions on 3rd down on 11 attempts. They stifled the Albany run game, allowing just 43 yards there.

Iowa State has already played twice this season and are 2-0. They upset #17 Kansas State in their opener in Dublin 24-21 and blasted South Dakota 55-7 last weekend. They held Kansas St to just 7 points through 3 quarters before allowing 2 passing touchdowns in the 4th quarter. They held the KSU run game to just over 100 yards and will need to be stout here against the rival Hawkeyes.

While Iowa St did put up 55 points last week, that is likely a mirage due to South Dakota’s abysmal defense. They will have a much tougher defense here against Iowa. We like the defenses to both step up here in the early in-state rivalry game as it has many times in the past. If we had to pick a side, we would lean with the Cyclones, given Rocco Becht’s experience and incredible start to this season.

Key Trends for Iowa vs Iowa State

• The total has gone UNDER in 15 of Iowa’s last 19 games against Iowa State.
• The total has gone UNDER in 13 of Iowa State’s last 18 games at home.
• The total has gone UNDER in 8 of Iowa’s last 11 games on the road.
• The total has gone UNDER in 17 of Iowa’s last 21 games played in week 2.

Saturday, September 5 at 3:30 PM	Spread	Money	Total
Baylor Bears	+8 (-113)	+235	O 59.5 (-109)
Auburn Tigers	-8 (-109)	-265	U 58.5 (-113)

Best Bet: Baylor +2.5

The Baylor Bears took a loss in their season opener at home versus Auburn 28-24. They could not figure out how to slow down QB, Jackson Arnold. He used his legs to do the most damage. He ran for over 130 yards and 2 touchdowns. He added just another 100 yards through the air on just 17 attempts. Outside of Arnold, no one else had much success against the Bears defense, but in the end, that is all Auburn needed. Sawyer Robertson looked decent under center for Baylor. He finished with over 400 yards and 3 touchdowns without an interception. The Baylor run game was nearly non-existent but due to them trailing most of the game, it is not much of a surprise.

The Mustangs are 1-0 after they beat up on lowly East Texas A&M 42-13. SMU racked up a total of 400 yards in the win and did so with a rather balanced attack. Kevin Jennings tossed 2 touchdowns and was picked off once. Romello Brinson had the brightest game as he finished with 7 catches for 121 yard and a touchdown. They are ranked inside the top 20 after the new polls came out but will have a serious test at home here against the visiting Bears.

This looks like a Baylor line to us. Unranked on the road against a top 20 team and catching less than a field goal number on the spread. The Baylor offense showed signs of explosiveness last week and the defense’s main issue was not being able to handle Jackson Arnold’s ability to run from the pocked. They won’t have that worry here against Kevin Jennings who is more of a pocket passer and will allow the Bears to lock in on their normal defensive style.

Key Trends for Baylor at SMU

• Baylor is 6-2 ATS in its last 8 games.
• Baylor is 10-3 ATS in its last 13 games played on a Saturday.
• SMU is 0-7 SU in its last 7 games against Baylor.
• SMU is 1-4 ATS in its last 5 games against an opponent in the Big 12 conference.

Best Bet: Kentucky +10.5

#20 Ole Miss is 1-0 after they demolished Georgia State in the 1st game of their season 63-7. In typical Lane Kiffin fashion, once they had a weaker opponent down, they did not let up. After taking the 25-7 lead after the 1st half, they went on to shut them out in the 2nd half 38-0. Austin Simmons looked alright in his 1st start replacing Jaxson Dart. He finished with 340 yards and 3 touchdowns but also tossed 2 interceptions. Kewan Lacy took his 16 carries for over 100 yards and 3 touchdowns. The defense held Georgia St to just 260 total yards and 2 of 15 on 3rd downs.

Kentucky had a much tougher time in their opener. They seemingly had the game in control most of the way but a later Toledo touchdown brought the game to within a score and a 2-point conversion away of a tie game. Kentucky relied heavily on their run game that racked up over 200 yards was much needed due to a passing game that saw just 85 yards gained through the air. QB, Zach Calzada will need to be better if the Wildcats hope to stay in this one against the Rebels. The defense was tough against the run but did give up over 300 yards through the air.

Ole Miss is certainly the more talented team but we do not trust Austin Simmons to play better here against the Wildcats than he did against a much weaker team in Georgia State. We believe the Rebels will make mistakes on some drives that will allow Kentucky to use their run game and control the ball enough to stay in this one at home. Rebels win but not by enough to cover the number.

Key Trends for Ole Miss at Kentucky

• UK is 6-1 ATS in its last 7 games when playing as the underdog.
• UK is 6-1 ATS in its last 7 games played in September.
• UK is 11-4 ATS in its last 15 games played in week 2.

Saturday, September 12 at 12:00 PM	Spread	Money	Total
Arizona State Sun Devils	+14.5 (-110)
Texas A&M Aggies	-14.5 (-110)

Best Bet: Arizona State -6.5

Kenny Dillingham was not pleased with how his Sun Devils performed in their opener. He demands more from his #12 ranked team. They defeated Northern Arizona 38-19. The offense converted n 3rd down just 2 times on 10 attempts and the defense gave up over 330 total yards. Sam Leavitt looked good both through the air and on the ground. He completed over 64% of his passes for over 250 yards and 2 touchdowns while also running for 73 yard and 2 touchdowns on the ground. Jordyn Tyson was spectacular in the win. He finished with 12 catches, 141 yard and 2 touchdowns.

Miss State dominated in the 2nd half of their opener against Southern Miss. Leading by just 3 points at the half, Miss State scored 24 unanswered points to start the 2nd half before Southern Miss scored a meaningless late touchdown. They converted on 3rd down at a nearly 65% clip. They also ran the ball well for just under 200 yards in the win. Blake Shapen was strong under center and completed over 75% of his passes in the win. On defense, they did have some trouble getting off the field. They allowed Southern Miss to convert on 3rd down 10 out of 19 times. However, they kept them out of the endzone for almost the entire 2nd half, which was the difference.

We love how Coach Dillingham handled the win last week. He knows that he must motivate his team for them to not take for granted their early wins over inferior teams. We believe they will come to Davis Wade Stadium to make a statement on Saturday. Those hiccups on 3rd down that the Bulldogs got away with last week will be exposed for points by Sam Leavitt and company.

Key Trends for Arizona State at Mississippi State

• ASU is 8-3 ATS in its last 11 games on the road.
• ASU is 7-1 ATS in its last 8 games when playing as the favorite.
• Miss St is 1-4 ATS in its last 5 games against an opponent in the Big 12 conference.
• Miss St is 1-7 ATS in its last 8 games played in September.