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Dodgers vs. Pirates Prediction: Ohtani Takes the Mound in Pittsburgh

Bryan Reynolds swinging at home plate for the Pittsburgh Pirates
Jason Martinak
Written by Jason Martinak
June 10, 2026

When the Los Angeles Dodgers visit PNC Park for the second game of this midweek series, they bring with them the most dominant pitcher in baseball and one of the most complete lineups in the modern era. Shohei Ohtani takes the ball on Wednesday night in Pittsburgh, and at 6-2 with a 0.74 ERA, the case for him as the frontrunner for the NL Cy Young is airtight. The Pittsburgh Pirates, sitting at 34-33 and clinging to a .500 record, will need everything to break right if they have any hope of stealing this game.

Los Angeles comes in at 43-24 on the season, leading the NL West and riding a five-game winning streak. Pittsburgh has been competitive at home, going 18-16 at PNC Park, but this matchup offers a jarring reality check. The Dodgers plated 10 runs in the seventh inning alone the night before, and their offense ranks first in the entire majors with a .784 team OPS. This is not a group that takes nights off.

The Ohtani Factor Makes the Odds Impossible to Ignore

The moneyline for this game opened with the Dodgers priced around -190 to -194 across major sportsbooks, and the number has moved slightly toward -186 on some books as the day has progressed. That implies roughly a 65 percent win probability for Los Angeles, which actually feels modest when you consider who is starting. The over/under sits at 8 runs, reflecting both the Dodgers' potent offense and the legitimate question of whether Pittsburgh can muster much against Ohtani.

The run line tells an interesting story. Los Angeles is -120 to cover the -1.5 spread, meaning sportsbooks give them a strong chance to win by multiple runs. That is backed up by Ohtani's track record this season: in his last start against Arizona, he threw six innings of two-hit, zero-run baseball while striking out six. His team has won four consecutive games in his starts, and he has been virtually untouchable since the calendar flipped to June.

For bettors looking at the under, Ohtani's ability to keep Pittsburgh off the board is a compelling argument. Jared Jones goes for the Pirates and he carries a 4.82 ERA, though his last outing was deceptively strong — five innings against Houston with zero earned runs allowed. The under 7.5 is available at +102 on some books, which offers legitimate value if you believe Ohtani stifles the Pittsburgh offense and Jones keeps the game somewhat competitive.

The Pitching Mismatch and What It Means for Pittsburgh

Jared Jones is 1-0 on the season, which looks impressive on the surface until you factor in the quality of opposition and the sample size. His 4.82 ERA tells a more honest story, and he'll be facing a Los Angeles lineup that is genuinely terrifying from top to bottom. Shohei Ohtani is listed in the lineup as DH, while Freddie Freeman, Kyle Tucker, and Max Muncy provide depth that would challenge any starting pitcher in the league.

Bryan Reynolds, Pittsburgh's best positional player, brings a .267 batting average and seven home runs on the year. He is the kind of contact hitter who can put something together against elite pitching — Reynolds has a switch-hitting approach that gives him better matchup flexibility than most of his teammates. Spencer Horwitz leads off for Pittsburgh and brings a left-handed swing that Ohtani typically neutralizes effectively. The Pirates have shown they can generate offense at home, ranking sixth in the majors in team OPS at .735, but keeping pace with the Dodgers in a game where Ohtani is dealing feels like an enormous ask.

Los Angeles has gone 3-2 in their last five games, which looks modest, but three of those contests came against the Angels. The Dodgers' road record sits at 21-12, confirming they travel as well as they play at Dodger Stadium. This is a franchise that does not allow the scenery to change their approach. When they have Ohtani pitching, they expect to win, and history suggests that is entirely reasonable.

Head-to-head, these franchises have split their recent history relatively evenly, going 6-6 in the last three seasons of meetings. But the Dodgers won 8 of the last 15 matchups overall, and this current Los Angeles roster is meaningfully better than the teams involved in most of those historical comparisons. Kyle Tucker, acquired in the offseason, adds another dimension that Pittsburgh's pitching staff has to account for.

The Dodgers are also coming off a ten-run seventh inning in Game 1 of this series, which speaks to the kind of offensive explosiveness that can make even a promising pitching performance feel fragile. Jones will likely need to limit walks and keep the ball out of the heart of the zone to survive deep into this game. One bad inning against this Los Angeles lineup can unravel a start in a hurry.

Prediction and Best Bet

Shohei Ohtani is having one of the most dominant pitching seasons in recent memory, and Pittsburgh simply does not have the firepower to overcome him tonight. The Dodgers' offense is first in baseball, their ace is at the absolute peak of his powers, and they are riding a five-game winning streak. Jared Jones has shown flashes but is not yet at a stage in his career to neutralize a lineup this deep.

  • Prediction: Dodgers 6, Pirates 2
  • Best Bet: Dodgers -1.5 run line (-120)

The -120 price on Los Angeles covering the run line is fair value here. Ohtani's four consecutive wins as a starter, combined with Pittsburgh's inability to generate big run totals against elite pitching, makes a multi-run Dodgers victory the most likely outcome. The moneyline at -186 prices in too much juice for the return, but the run line at -120 still offers a compelling risk-reward proposition on a night when the talent gap is this wide.

[game_odds league="mlb" team="Los Angeles Dodgers" date="2026-06-10"]

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