The NFL’s last two undefeated teams are both in action for Week 5, facing tough tests to remain that way. The same is true of the two remaining winless teams, facing uphill battles to claim their first victory of the 2023 season.
Which of these teams have the best chance of seeing their current streak end? Read on to see the odds for each matchup of the NFL Week 5 schedule.
After a closer-than-expected OT loss to Philadelphia last week, the Washington Commanders (2-2) look to return to the win column this week against the winless Chicago Bears (0-4).
The Bears, meanwhile, are owners of the second-worst defense in the league after surrendering 1,500 yards of offense through the first four weeks. The over/under total for this contest starts at 44 points.
For the first time in NFL history, one franchise – the Jacksonville Jaguars (2-2) – will play back-to-back games in London. After winning last week, the Jags will face a Buffalo Bills (3-1) team that travels across the pond fresh off a victory over a previously undefeated Miami team.
Will the extended stay help Jacksonville pull off the upset? This game has an over/under total starting at 49 points.
A pair of teams needing wins to maintain their playoff hopes meet this week when the New Orleans Saints (2-2) travel north to face the New England Patriots (1-3) Sunday.
New Orleans opened the season by winning both contests before Derek Carr suffered a shoulder injury in Week 3. Since then, the Saints have been outscored 44-9 in the last five quarters of action.
New England, meanwhile, was outscored 38-3 Sunday by Dallas to produce the most lopsided loss in Bill Belichick’s storied coaching career. The over/under for this contest begins at 40 points.
An AFC South battle – potentially for first place – takes place in Indianapolis during Week 5 when the Colts (2-2) host the Tennessee Titans (2-2). Indianapolis had won two straight games before losing to the Los Angeles Rams in OT Sunday – their second consecutive overtime game.
Tennessee throttled the Cincinnati Bengals in Week 4, now having both home games they’ve played in 2023. This contest features a higher-than-expected 42.5 over/under points total line.
A battle of AFC North leaders occurs during Week 5 as the Baltimore Ravens (3-1) hit the road to face the Pittsburgh Steelers (2-2). Baltimore’s only loss came in a Week 3 OT game against the Colts while Pittsburgh’s two wins have been sandwiched by losses of more than 20 points.
Which Steelers team shows up will determine how competitive this game – showcasing Week 5’s lowest over/under point total at 37.5 points – will be.
The NFL’s other winless team – the Carolina Panthers (0-4) – hit the road to face a tough test against the Detroit Lions (3-1). The Panthers are among the worst teams in the NFL against the run, yielding 4.7 yards per rush and over 136 yards on average through their first four games.
Offensively, Detroit is among the Top 10 teams this year rushing the ball, averaging a little over 4 yards per rush and over 110 yards per game. The over/under on this game starts at 44.5 total points.
A pair of 2-2 teams heading in opposite directions collide when the Houston Texans face off against the Atlanta Falcons Sunday. Houston has won their last two contests by 20 or more points.
Atlanta, who returns from their London contest – has dropped two straight by more than 14 points. With an over/under starting at 41 points, this contest could easily best the over figure as both teams sport streaky defensive units.
This week’s largest spread belongs to the New York Giants (1-3), who are giving up more than 10 points against the Miami Dolphins (3-1). Fresh off their Monday night loss, the Giants will look to resurrect their offense against a Miami team that has the fifth-most points so far this NFL season.
Offensively, the Dolphins have averaged 500 yards per contest through the first four weeks and have scored a NFL best 150 points in 2023. With that in mind, the over/under total line starts at 49.5 points, making this an enticing offer for bettors.
Two disappointing teams desperately seeking wins lock up Sunday afternoon when the Cincinnati Bengals (1-3) square off against the Arizona Cardinals (1-3). Cincinnati’s offense ranks last in the league, garnering just over 1,000 yards through their first four games.
While Arizona’s offense remains competent without Kyler Murray, the Cardinals’ defense ranks in the bottom 10 in yards allowed passing and rushing. Although this game could become a shoot-out, oddsmakers have the over/under total set at 44.5 points.
The undefeated Philadelphia Eagles (4-0) look to remain perfect as they go across the country to take on the Los Angeles Rams (2-2). These two exciting offenses collide in the Eagles’ first-ever visit to SoFi Stadium.
The Eagles possess the league’s second-ranked rushing attack and have more rushing attempts than any other team. Los Angeles, meanwhile, prefers the air thanks to their second-best standings with 1,229 passing yards. The over/under for this contest starts at.50.5 points.
Another game involving a pair of 1-3 teams kicks off in Colorado Sunday afternoon as the Denver Broncos face the New York Jets.
While both teams own one lopsided loss, six of the combined eight games these teams have played came down to six points or less, including each team’s victory. The over/under total for this game starts at 43 points.
Two high-octane offenses collide this week when the Kansas City Chiefs (3-1) take on the Minnesota Vikings (1-3) Sunday. The Chiefs have relied on Isiah Pacheco this year as the RB leads the team with 65 touches for 360 combined yards.
Minnesota airs out the ball, and both QB Kirk Cousins and WR Justin Jefferson are league leaders through the first four games. Befitting a game that could light up the scoreboard, the over/under for this matchup is league’s highest at 53 points.
The game of the week is also the Sunday Night primetime matchup as the Dallas Cowboys (3-1) head to California to take on the San Francisco 49ers (4-0). In spite of an embarrassing upset in Week 3, Dallas has looked dominant to start the 2023 NFL season.
San Francisco, meanwhile, has won three of their first four contests by 18 or more points. This exciting Sunday nightcap has a starting over/under total at 45 points.
Week 5’s final contest features the Green Bay Packers (2-2) against the Las Vegas Raiders (1-3). Green Bay enters the Monday Night contest with an extended break as they enjoy an 11-day break from competition.
The Raiders enter the contest without a clear answer at QB with Jimmy Garropolo still under concussion protocols. At 44.5 points, oddsmakers have perhaps overvalued each team’s offensive prowess in a defensive-first contest.
Bye week: Los Angeles Chargers, Tampa Bay Buccaneers, Seattle Seahawks, Cleveland Browns
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Earnest is a 25-year veteran of the newspaper industry. He's spent the majority of his early years working as a sports reporter and editor. He made the move back to the digital world in 2022, joining EatWatchBet as a senior writer. Ernie covers college football betting, fantasy football, and NFL betting for EatWatchBet.