The first week of NFL action proved that oddsmakers are guessing just as much as you were last week. Vegas was only 9-7 overall in setting the lines for the season-opening games, showing that even people who get paid to do this can succumb to preseason hype.
There’s no hype here as we review the NFL’s Week 2 odds. Enjoy all of the action this week! Good luck!
| Monday, November 9 at 8:15 PM | Spread | Money | Total |
| Buffalo Bills |  -3 (-118) |  -175 |  O 45 (-112) |
| Minnesota Vikings | +3 (-107) | +150 |  U 44.5 (-112) |
Bills at Dolphins
The Miami Dolphins (1-0) face the Buffalo Bills (1-0) in a critical AFC East showdown, where both teams are battling for divisional supremacy. With the Dolphins’ high-powered offense going up against the Bills’ stingy defense, this game could have significant playoff implications.
| Sunday, November 8 at 1:00 PM | Spread | Money | Total |
| Dallas Cowboys | -6 (-112) | -230 | O 51.5 (-106) |
| Indianapolis Colts | +6 (-112) |  +215 | U 51.5 (-117) |
Saints at Cowboys
The New Orleans Saints (1-0) face the Dallas Cowboys (1-0) in a thrilling matchup, with the Saints coming off a dominant Week 1 performance where they scored the most points in the league. The Cowboys’ defense will be tested to slow down the Saints’ high-powered offense and build on their early-season success.
| Sunday, November 8 at 1:00 PM | Spread | Money | Total |
| Detroit Lions | -7 (-115) | -325 | O 50.5 (-105) |
| Miami Dolphins | +7 (-115) | +285 | U 50 (-108) |
Bucs at Lions
The Tampa Bay Buccaneers (1-0) take on the Detroit Lions (1-0) in a matchup of old NFC North rivals, both aiming to solidify their playoff aspirations. With both teams showing promise early in the season, this game could be pivotal in shaping the postseason race.
| Sunday, November 8 at 1:00 PM | Spread | Money | Total |
| Dallas Cowboys | -6 (-112) | -230 | O 51.5 (-106) |
| Indianapolis Colts | +6 (-112) | +215 | U 51.5 (-117) |
Colts at Packers
The Indianapolis Colts (0-1) face the Green Bay Packers (0-1) in a crucial matchup, with the Packers navigating the absence of quarterback Jordan Love, who is out 3-6 weeks due to injury. The Colts will look to capitalize on Green Bay’s uncertainty at quarterback as both teams fight to stay competitive in their divisions.
| Sunday, November 15 at 1:00 PM | Spread | Money | Total |
| Jacksonville Jaguars | -10.5 (-105) | -530 | O 45.5 (-110) |
| Tennessee Titans | +10.5 (-115) | +460 | U 44.5 (-105) |
Jets at Titans
The New York Jets (0-1) take on the Tennessee Titans (0-1) in a compelling matchup, where the Titans’ evolving offense will face a stiff test against the Jets’ physical defense. Both teams are eager to build momentum, making this a crucial game for playoff positioning early in the season.
| Monday, November 9 at 8:15 PM | Spread | Money | Total |
| Buffalo Bills | -3 (-118) | -175 | O 45 (-112) |
| Minnesota Vikings | +3 (-107) | +150 | U 44.5 (-112) |
49ers at Vikings
The San Francisco 49ers (1-0) take on the Minnesota Vikings (1-0) in a key matchup, with the 49ers’ offense facing uncertainty as star running back Christian McCaffrey’s status remains in doubt. The Vikings will look to exploit any potential weakness in the 49ers’ ground game as both teams aim to make a statement early in the season.
| Sunday, November 8 at 4:25 PM | Spread | Money | Total |
| Arizona Cardinals | +9 (-112) | +350 | O 39.5 (-110) |
| Seattle Seahawks | -9 (-109) | -420 | U 39.5 (-110) |
Seahawks at Pats
The Seattle Seahawks (1-0) face the New England Patriots (1-0) in a defensive showdown, with sportsbooks projecting the lowest total points for Week 2 at 37.5. Both teams will rely on their defenses to control the game, as scoring opportunities are expected to be limited in this affair.
| Sunday, November 8 at 1:00 PM | Spread | Money | Total |
| Los Angeles Rams | -4.5 (-115) | -225 | O 48.5 (-105) |
| Washington Commanders | +4.5 (-110) | +190 | U 48 (-112) |
Giants at Commanders
The New York Giants (0-1) and Washington Commanders (0-1) clash in a pivotal NFC East matchup, where both teams are looking to make a statement early in the season. With divisional rivalries intensifying, this game is crucial for both teams to set the tone for the remainder of the year.
| Sunday, November 8 at 1:00 PM | Spread | Money | Total |
| Denver Broncos | -2.5 (-120) | -142 | O 44.5 (-105) |
| Carolina Panthers | +2.5 (-105) | +130 | U 44 (-110) |
Chargers at Panthers
The Los Angeles Chargers (1-0) take on the Carolina Panthers (0-1) as the Panthers come off a Week 1 performance where they allowed the most points in the league. The Chargers will look to capitalize on this defensive vulnerability and build on their own early-season momentum.
| Sunday, November 8 at 1:00 PM | Spread | Money | Total |
| Cleveland Browns | +3 (-112) | +145 | O 43.5 (100) |
| New Orleans Saints | -3 (-115) | -162 | U 42.5 (-110) |
Browns at Jags
The Cleveland Browns (0-1) face the Jacksonville Jaguars (0-1) in a critical matchup, with both teams looking to avoid falling to 0-2. Historically, teams starting 0-2 have a tough road ahead, with only 31 of the 270 since 1990 making it to the playoffs, adding extra urgency to this game.
| Monday, November 16 at 8:15 PM | Spread | Money | Total |
| Los Angeles Chargers | +1.5 (-115) | +108 | O 38.5 (-110) |
| Baltimore Ravens | -1.5 (-110) | -118 | U 37.5 (-110) |
Raiders at Ravens
The Las Vegas Raiders (0-1) take on the Baltimore Ravens (0-1) in a matchup where the Raiders will aim to challenge the Ravens’ dynamic defense with their improving offense. Both teams are looking to make a statement and secure a crucial win early in the season to build momentum for the playoffs.
| Sunday, November 8 at 4:25 PM | Spread | Money | Total |
| Arizona Cardinals | +9 (-112) | +350 | O 39.5 (-110) |
| Seattle Seahawks | -9 (-109) | -420 | U 39.5 (-110) |
Rams at Cardinals
The Los Angeles Rams (0-1) face the Arizona Cardinals (0-1) in a key NFC West showdown, with both teams eager to assert themselves in a competitive division. The matchup will highlight the Rams’ potent offense against the Cardinals’ defensive strategies, as each team aims to gain an early edge in the division race.
| Sunday, November 15 at 8:20 PM | Spread | Money | Total |
| Pittsburgh Steelers | +3.5 (-121) | +150 | O 47.5 (-107) |
| Cincinnati Bengals | -3.5 (-110) | -168 | U 47.5 (-114) |
Steelers at Broncos
The Pittsburgh Steelers (1-0) take on the Denver Broncos (0-1) with quarterback Justin Fields expected to start for the Steelers. Fields’ second game under center would be a focal point of this matchup as he looks to lead the Steelers’ offense against the Broncos’ improving defense in a crucial matchup.
| Sunday, November 8 at 9:30 AM | Spread | Money | Total |
| Cincinnati Bengals | -3 (-121) | -166 | O 52.5 (-105) |
| Atlanta Falcons | +3 (-109) | +148 | U 52.5 (-115) |
Bengals at Chiefs
The Cincinnati Bengals (0-1) visit the Kansas City Chiefs (1-0) in a highly anticipated rematch of the 2022 AFC Championship game. Both teams are eager to settle the score from their previous playoff encounters, with the Chiefs looking to assert their dominance and the Bengals aiming for redemption.
| Sunday, November 8 at 8:20 PM | Spread | Money | Total |
| Tampa Bay Buccaneers | +6.5 (-115) | +240 | O 47.5 (-105) |
| Chicago Bears | -6.5 (-105) | -270 | U 47.5 (-115) |
Bears at Texans
The Chicago Bears (1-0) visit the Houston Texans (1-0) as the NFC North squad continues their search for their first offensive touchdown of the season. No. 1 overall pick Caleb Williams will aim to spark their struggling offense in his first primetime contest. The Texans will look to capitalize on the Bears’ offensive woes and secure a crucial win at home.
| Sunday, November 8 at 9:30 AM | Spread | Money | Total |
| Cincinnati Bengals | -3 (-121) | -166 | O 52.5 (-105) |
| Atlanta Falcons | +3 (-109) | +148 | U 52.5 (-115) |
Falcons at Eagles
The Atlanta Falcons (0-1) take on the Philadelphia Eagles (1-0) in a thrilling Monday Night Football matchup. Both teams are eager to make a statement in prime time, with the Falcons looking to capitalize on their recent momentum and the Eagles aiming to solidify their status as one of the NFC’s top contenders.
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