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Midwest Region Preview: 3 Best Bets to Make Sweet 16

Midwest Region Preview 3 Best Bets to Make Sweet 16
Bill Christy
Written by Bill Christy
March 15, 2023

21+ to wager. Please Gamble Responsibly. Call 1-800-NEXT-STEP (AZ), 1-800-522-4700 (KS, NV), 1-800-BETS-OFF (IA), 1-800-270-7117 for confidential help (MI). Gambling problem? Call 1-800-GAMBLER. Call 877-8-HOPENY or text HOPENY (467369) (NY) Call 1-800-327-5050 (MA).

Houston has been arguably the most dominant team in college basketball this season. The Cougars are the #1 seed in the Midwest Region, and they look primed to make a Final Four run. There are some talented teams in this region, but this is one of the weaker sections of the bracket.

Ready to crush March Madness? Check out our Midwest Region Preview, which includes 3 Best Bets to Make the Sweet 16. Best of luck with all of your picks!

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Best Bet: Texas Longhorns

Best Available Odds: -142 at FanDuel

The Longhorns capped off a great season with a Big 12 tournament title as they demolished Kansas in the final. They check all the boxes to be a true contender for the NCAA title this tourney. Now, they will have a tough matchup in the 2nd round against either Texas A&M or Penn State.

That said, we believe getting them at just -150 here is worth the early play instead of waiting to see what the money line comes out at against either of those teams. Colgate is their 1st opponent, but we are not concerned with them pulling off the 15-seeded upset here.

Best Value Bet: Xavier Musketeers

Best Available Odds: +106 at FanDuel

Xavier is not the best that the Big East has to offer, but they do get favorable matchups in the 1st two rounds. Kennesaw State is already an 11.5-point underdog for the 1st game, and Xavier would then get either Iowa State or the winner of Pitt and Mississippi State.

Whomever Xavier plays in the 2nd round, they will be at least a 3-5 point favorite and make our money line much worse than the +105 we are getting here. Give us the Musketeers as our best value bet from the Midwest.

Best Longshot: Miami Hurricanes

Best Available Odds: +194 at FanDuel

This Miami team has the ability to hang with the best teams in the country. Their ability on the offensive end to shoot effectively both inside and outside of the 3-point line makes them an extremely dangerous team.

Drake will be no pushover for them in the 1st round, but Indiana is one of the most “Jekyll and Hyde” teams in the country. We believe Miami will be in the Sweet 16, and Drake will be the tougher of the 2 games. The Canes could be poised for an even deeper run in the Big Dance if they can get hot.

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21+ to wager. Please Gamble Responsibly. Call 1-800-NEXT-STEP (AZ), 1-800-522-4700 (KS, NV), 1-800-BETS-OFF (IA), 1-800-270-7117 for confidential help (MI). Gambling problem? Call 1-800-GAMBLER. Call 877-8-HOPENY or text HOPENY (467369) (NY) Call 1-800-327-5050 (MA).

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